Study of a new investigational compound that may possibly be used for the treatment of cancer


  • Your weight is between 50 and 100 kg and your Body Mass Index (BMI) is between 18.5 and 30.0 kg/m2. The BMI reflects the relation between your body weight in kilograms and your height in meters.
  • Both non-smokers and light smokers are allowed to participate in this study.
  • You are only allowed to participate in this study if you meet one of the following:
    • you are vasectomized  at least 6 months before the start of the study;
    • you use a condom and your female partner an intrauterine device;
    • you use a condom and your female partner an additional hormonal contraceptive (e.g. the pill);
    • your female partner have had a bilateral tubal occlusion;
    • you are true abstinent during the study and during the 90 following days after the last dosing.
  • To determine if you are suitable to participate in this study, you will undergo a medical screening.
Calculate BMI


You will receive a gross compensation of €1.024,- for full participation in one of the mentioned groups above.

Travelling expenses will be reimbursed based on the distance traveled (€0,19 net per kilometer) with a minimum of €12,- and a maximum of €160,- (840 kilometers) per return, regardless of the mode of transportation.

Period of stay and research

For both groups 1a and 1b the study consists of 1 period were you will stay for 7 days (6 nights) in our research facility in Groningen (location UMCG). The follow-up visit will take place 10 days after the last dosing, the appointment for this follow-up visit will be made during your stay.

Please note: You have to be available for all dates mentioned to be able to participate in this study. These are the currently planned dates; however, these may be subject to change.


Group 1b


7 days stay

  • 28 May 2018 up to and including 3 Jun 2018
€ 1.024,- Select

Group 1b


7 days stay

  • 29 May 2018 up to and including 4 Jun 2018
€ 1.024,- Select