PRA-180391 Buildup of abnormal proteins € 1.043,-

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Description

Study of a new investigational compound that may eventually be used for the treatment of buildup of abnormal proteins in organs (amyloidosis)

Requested participants

  • M/F, healthy, 18 - 65 years old
  • Non-smokers only

Duration and visits

  • 4 days stay
  • 4 short visits

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Research details

Particulars

  • You are a non-smoker.
  • Your weight is between 45kg and 120 kg and your Body Mass Index (BMI) is between 18.0 and 32.0 kg/m2. The BMI reflects the relation between your body weight in kilograms and your height in meters.
  • As a male you are only allowed to participate in this study if you use a condom. 
  • As a female you are only allowed to participate in this study if you:
    • Have been surgically sterilized at least 6 months ago;
    • Or have been postmenopausal for at least two years;
    • Or you used at least 60 days before the dosing hormonal contraception (e.g. the pill or intrauterine device);
    • Or use a condom;
    • Or your male partner has been vasectomized at least 6 months before the start of the study;
  • To determine if you are eligible to participate in this study, you will undergo a medical screening.
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Compensation

You will receive a gross compensation of € 1.043,- for complete participation in one of the above groups.

Travelling expenses will be reimbursed based on the distance traveled (€ 0,19 net per kilometer) with a minimum of € 12,- and a maximum of € 160,- (840 kilometers) per return, irrespective of the method of transportation.

Period of stay and research

For all groups the study consists of 1 period were you will stay for 4 days (3 nights) in our research facility in Groningen (location Martini), followed by 4 short visits to our research facility.

Please note: You have to be available for the entire period to participate in this study. These are the currently planned dates; however, these may be subject to change. If the dates do change you will be notified as soon as possible.

 

Group 2b

€ 1.043,-

4 days stay

  • 2 Sep 2018 up to and including 5 Sep 2018

short stay

Inapplicable

short visit

  • 9 Sep 2018
  • 16 Sep 2018
  • 30 Sep 2018
  • 21 Oct 2018

Group 2c

€ 1.043,-

4 days stay

  • 3 Sep 2018 up to and including 6 Sep 2018

short stay

Inapplicable

short visit

  • 10 Sep 2018
  • 17 Sep 2018
  • 1 Oct 2018
  • 22 Oct 2018

Group 1a

€ 1.043,-

4 days stay

  • 23 Jul 2018 up to and including 26 Jul 2018

short stay

Inapplicable

short visit

  • 30 Jul 2018
  • 6 Aug 2018
  • 20 Aug 2018
  • 10 Sep 2018
Group full

Group 1b

€ 1.043,-

4 days stay

  • 25 Jul 2018 up to and including 28 Jul 2018

short stay

Inapplicable

short visit

  • 1 Aug 2018
  • 8 Aug 2018
  • 22 Aug 2018
  • 12 Sep 2018
Group full

Group 1c

€ 1.043,-

4 days stay

  • 26 Jul 2018 up to and including 29 Jul 2018

short stay

Inapplicable

short visit

  • 2 Aug 2018
  • 9 Aug 2018
  • 23 Aug 2018
  • 13 Sep 2018
Group full

Group 2a

€ 1.043,-

4 days stay

  • 30 Aug 2018 up to and including 2 Sep 2018

short stay

Inapplicable

short visit

  • 6 Sep 2018
  • 13 Sep 2018
  • 27 Sep 2018
  • 18 Oct 2018
Group full

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